Planning while Believing to Know

Over the last few years, the concept of Artificial Intelligence (AI) has become essential in our daily life and in several working scenarios. Among the various branches of AI, automated planning and the study of multi-agent systems are central research fields. This thesis focuses on a combination of these two areas: that is, a specialized kind of planning known as Multi-agent Epistemic Planning. This field of research is concentrated on all those scenarios where agents, reasoning in the space of knowledge/beliefs, try to find a plan to reach a desirable state from a starting one. This requires agents able to reason about her/his and others’ knowledge/beliefs and, therefore, capable of performing epistemic reasoning. Being aware of the information flows and the others’ states of mind is, in fact, a key aspect in several planning situations. That is why developing autonomous agents, that can reason considering the perspectives of their peers, is paramount to model a variety of real-world domains. The objective of our work is to formalize an environment where a complete characterization of the agents’ knowledge/beliefs interactions and updates are possible. In particular, we achieved such a goal by defining a new action-based language for Multi-agent Epistemic Planning and implementing epistemic planners based on it. These solvers, flexible enough to reason about various domains and different nuances of knowledge/belief update, can provide a solid base for further research on epistemic reasoning or real-base applications. This dissertation also proposes the design of a more general epistemic planning architecture. This architecture, following famous cognitive theories, tries to emulate some characteristics of the human decision-making process. In particular, we envisioned a system composed of several solving processes, each one with its own trade-off between efficiency and correctness, which are arbitrated by a meta-cognitive module

Acute respiratory distress syndrome

Since its first description, the acute respiratory distress syndrome (ARDS) has been acknowledged to be a major clinical problem in respiratory medicine. From July 2015 to July 2016 almost 300 indexed articles were published on ARDS. This review summarises only eight of them as an arbitrary overview of clinical relevance: definition and epidemiology, risk factors, prevention and treatment. A strict application of definition criteria is crucial, but the diverse resource-setting scenarios foster geographic variability and contrasting outcome data. A large international multicentre prospective cohort study including 50 countries across five continents reported that ARDS is underdiagnosed, and there is potential for improvement in its management. Furthermore, epidemiological data from low-income countries suggest that a revision of the current definition of ARDS is needed in order to improve its recognition and global clinical outcome. In addition to the well-known risk-factors for ARDS, exposure to high ozone levels and low vitamin D plasma concentrations were found to be predisposing circumstances. Drug-based preventive strategies remain a major challenge, since two recent trials on aspirin and statins failed to reduce the incidence in at-risk patients. A new disease-modifying therapy is awaited: some recent studies promised to improve the prognosis of ARDS, but mortality and disabling complications are still high in survivors in intensive care

Corporate control and executive selection

In firms with concentrated ownership the controlling shareholder may pursue nonmonetary private returns, such as electoral goals in a firmcontrolled by politicians or family prestige in family firms.We use a simple theoretical model to analyze how this mechanism affects the selection of executives and, through this, the firm’s productivity compared to a benchmark where the owner only cares about the value of the firm.We discuss identification and derive two structural estimates of the model, based on different sample moments. The estimates, based on a matched employer–employee data set of Italian firms, suggest that private returns are larger in family- and government-controlled firms than in firms controlled by a conglomerate or by a foreign entity. The resulting distortion in executive selection can account for total factor productivity differentials between control types of up to 10%

Analysis of tissue surrounding thyroid nodules by ultrasound digital images

Since US is not easily reproducible, the digital image analysis (IA) has been proposed so that the image evaluation is not subjective. In fact, IA meets the criteria of objectivity, accurateness, and reproducibility by a matrix of pixels whose value is displayed in a gray level. This study aims at evaluating via IA the tissue surrounding a thyroid nodule (backyard tissue, BT) from goitres with benign (b-BT) and malignant (m-BT) lesions. Sixty-nine US images of thyroid nodules surrounded by adequate thyroid tissue was classified as normoechoic and homogeneous were enrolled as study group. Forty-three US images from normal thyroid (NT) glands were included as controls. Digital images of 800 × 652 pixels were acquired at a resolution of eight bits with a 256 gray levels depth. By one-way ANOVA, the 43 NT glands were not statistically different (P = 0.91). Mean gray level of normal glands was significantly higher than b-BT (P = 0.026), and m-BT (P = 0.0001), while no difference was found between b-BT and m-BT (P = 0.321). NT tissue boundary external to the nodule was found at 6.0 ± 0.5 mm in cancers and 4.0 ± 0.5 mm in benignancies (P = 0.001). These data should indicate that the tissue surrounding a thyroid nodule may be damaged even when assessed as normal by US. This is of interest to investigate the extranodular effects of thyroid tumors

Green bean biofortification for Si through soilless cultivation: Plant response and Si bioaccessibility in pods

Food plants biofortification for micronutrients is a tool for the nutritional value improvement of food. Soilless cultivation systems, with the optimal control of plant nutrition, represent a potential effective technique to increase the beneficial element content in plant tissues. Silicon (Si), which proper intake is recently recommended for its beneficial effects on bone health, presents good absorption in intestinal tract from green bean, a high-value vegetable crop. In this study we aimed to obtain Si biofortified green bean pods by using a Si-enriched nutrient solution in soilless system conditions, and to assess the influence of boiling and steaming cooking methods on Si content, color parameters and Si bioaccessibility (by using an in vitro digestion process) of pods. The Si concentration of pods was almost tripled as a result of the biofortification process, while the overall crop performance was not negatively influenced. The Si content of biofortified pods was higher than unbiofortified also after cooking, despite the cooking method used. Silicon bioaccessibility in cooked pods was more than tripled as a result of biofortification, while the process did not affect the visual quality of the product. Our results demonstrated that soilless cultivation can be successfully used for green bean Si biofortification

Supplementary Far-Red Light Did Not Affect Tomato Plant Growth or Yield under Mediterranean Greenhouse Conditions

In the Mediterranean region, tomato plants are often cultivated in two short cycles per year to avoid the heat of summer and the low solar radiation of winter. Supplementary light (SL) makes it possible to cultivate during the dark season. In this experiment, a tomato F1 hybrid cultivar DRW7723 was cultivated in a greenhouse for a fall-winter cycle. After transplant, light emitting diode (LED) interlighting, with two light spectra (red + blue vs. red + blue + far-red) was applied as SL. Plant growth, yield, gas exchange, nutrient solution (NS) consumption, and fruit quality were analyzed. In general, the eects of adding far-red radiation were not visible on the parameters analyzed, although the yield was 27% higher in plants grown with SL than those grown without. Tomatoes had the same average fresh weight between SL treatments, but the plants grown with SL produced 16% more fruits than control. Fruit quality, gas exchange and NS uptake were not influenced by the addition of far-red light. Interlighting is, therefore, a valid technique to increase fruit production in winter but at our latitude the eects of adding far-red radiation are mitigated by available sunlight

Corporate control and executive selection

We present a model in which the owner of the firm enjoys a private benefit from developing a personal relationship with the executives. This may lead the owner to retain a senior executive in office even though a more productive replacement is available. The model shows that the private returns of the employment relationship distort executive selection, reducing the executives’ average ability and the firm productivity. We estimate the structural parameters of the model using a panel of Italian firms with information on the nature of the controlling shareholder, matched with individual records of their executives. These estimates are used to quantify the relevance of private returns and the related productivity gap across firms characterized by four different types of ownership: government, family, conglomerate and foreign. We find that private returns are large in family and government controlled firms, while smaller with other ownership types. The resulting distortion in executive selection can account for TFP differentials between control types of about 10%. The structural estimates are fully consistent with a set of model-based OLS regressions, even though the sample moments used by the two approaches are different

Analysis of Helicopter Activities in Forest Fire-Fighting

In Southern European countries wildfires are the most natural threat to forests and wooded areas. Over the last decade, public and scientific debates on forest fire management have increased. Helicopters and airtankers are extremely effective fire suppression means, but they are also very expensive. Studies on the improved performance of suppression for the enhancement of firefighting organization are still needed. Consequently to make a plan for the distribution of financial resources to be divided between fire suppression and fire prevention actions in terms of fuel management is not possible. The aim of this study is to compare the helicopter’s forest fire-fighting activity in Tuscany (central Italy) over two periods: between 1998–2000 and 2001–2005 when five and ten helicopters were respectively assigned. For both periods (1998–2000 and 2001–2005) the following were analyzed: the number of forest fires and the burned area with or without helicopter intervention and the position of the helicopter bases in relation to the fire. The results showed that a fleet of 10 helicopters is oversized, in relation to the fire regime of Tuscany, suggesting the need to evaluate a reduction in the fleet. Financial resources may be thus made available for more profitable fire prevention activities, such as, active fuel management. The results also showed where there is the need to improve the helicopter efficiency via the re–management as regards the positioning of their bases

Identification of D179H, a novel missense GJB2 mutation in a Western Sicily family

The main purpose of this study was to describe a novel missense mutation (p.D179H) found in a Western Sicily family and to examine the genetic and audiologic profiles of all family members by performing a GJB2 and GJB6 mutations analysis and a complete audiologic assessment. The proband was a 3-month-old infant with a congenital profound sensorineural hearing loss; direct sequencing of the GJB2 revealed the presence of a c.35delG mutation in the heterozygous state and a heterozygous G[C transition at nucleotide 535 in trans; this novel mutation, called p.D179H, resulted in an aspartic acid to histidine change at codon 179. It was also evidenced in the heterozygous state in two members of this family, both with normal hearing. No GJB6 mutations were evidenced in all subjects studied. Considering the genotypic and phenotypic analysis of all family members, we suggest, differently from the p.D179 N mutation previously reported, a recessive mode of inheritance. Functional studies on p.D179H have to be performed to confirm our hypothesis